Title : Discovery of oxysterol-derived pharmacological chaperones for NPC1: implication for the existence of second sterol-binding site.

Pub. Date : 2013 Mar 21

PMID : 23521797






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Discovery of oxysterol-derived pharmacological chaperones for NPC1: implication for the existence of second sterol-binding site. Sterols NPC intracellular cholesterol transporter 1 Homo sapiens
2 These oxysterol derivatives bind to a domain of NPC1 that is different from the known N-terminal sterol-binding domain; i.e., there is an additional sterol-binding site on NPC1. Sterols NPC intracellular cholesterol transporter 1 Homo sapiens
3 These oxysterol derivatives bind to a domain of NPC1 that is different from the known N-terminal sterol-binding domain; i.e., there is an additional sterol-binding site on NPC1. Sterols NPC intracellular cholesterol transporter 1 Homo sapiens
4 These oxysterol derivatives bind to a domain of NPC1 that is different from the known N-terminal sterol-binding domain; i.e., there is an additional sterol-binding site on NPC1. Sterols NPC intracellular cholesterol transporter 1 Homo sapiens