Title : A specific inhibitor of protein kinase C induces differentiation of neuroblastoma cells.

Pub. Date : 1990 Jun 15

PMID : 2351657






2 Functional Relationships(s)
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1 We show that 1-(5-isoquinolinylsulfonyl)-2-methylpiperazine (H7), the more specific inhibitor of protein kinase C known, induces morphological and functional differentiation of neuro 2a cells, as indicated by the marked increase in the number of neurites/cell and in acetylcholinesterase activity. 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine acetylcholinesterase Mus musculus
2 We show that 1-(5-isoquinolinylsulfonyl)-2-methylpiperazine (H7), the more specific inhibitor of protein kinase C known, induces morphological and functional differentiation of neuro 2a cells, as indicated by the marked increase in the number of neurites/cell and in acetylcholinesterase activity. 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine acetylcholinesterase Mus musculus