Title : Role of MUTYH in human cancer.

Pub. Date : 2013 Mar-Apr

PMID : 23507534






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 MUTYH, a human ortholog of MutY, is a post-replicative DNA glycosylase, highly conserved throughout evolution, involved in the correction of mismatches resulting from a faulty replication of the oxidized base 8-hydroxyguanine (8-oxodG). 8-ohdg mutY DNA glycosylase Homo sapiens
2 In particular removal of adenine from A:8-oxodG mispairs by MUTYH activity is followed by error-free base excision repair (BER) events, leading to the formation of C:8-oxodG base pairs. 8-ohdg mutY DNA glycosylase Homo sapiens
3 In particular removal of adenine from A:8-oxodG mispairs by MUTYH activity is followed by error-free base excision repair (BER) events, leading to the formation of C:8-oxodG base pairs. 8-ohdg mutY DNA glycosylase Homo sapiens