Title : Aspirin: a review of its neurobiological properties and therapeutic potential for mental illness.

Pub. Date : 2013 Mar 18

PMID : 23506529






1 Functional Relationships(s)
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1 Aspirin is a non-steroidal anti-inflammatory drug that is an irreversible inhibitor of both cyclooxygenase (COX)-1 and COX-2, It stimulates endogenous production of anti-inflammatory regulatory "braking signals", including lipoxins, which dampen the inflammatory response and reduce levels of inflammatory biomarkers, including C-reactive protein, tumor necrosis factor-alpha and interleukin (IL)--6, but not negative immunoregulatory cytokines, such as IL-4 and IL-10. Aspirin interleukin 6 Homo sapiens