Title : Endoplasmic reticulum stress induced by 2-deoxyglucose but not glucose starvation activates AMPK through CaMKKβ leading to autophagy.

Pub. Date : 2013 May 15

PMID : 23500541






1 Functional Relationships(s)
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1 In addition to ER stress, GS also stimulates autophagy through lowering ATP and activating the canonical LKB1-AMPK energy sensing pathway as well as through increasing reactive oxygen species resulting in the activation of ERK. Reactive Oxygen Species mitogen-activated protein kinase 1 Homo sapiens