Pub. Date : 2013 Mar 22
PMID : 23485467
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | While IDH1 catalyzes the oxidative carboxylation of isocitrate to alpha-ketoglutarate in cytosol, mutated IDH1 proteins possess the ability to change alpha-ketoglutarate into onco-metabolite R(-)-2-hydroxyglutarate (2-HG). | isocitric acid | isocitrate dehydrogenase 1 (NADP+), soluble | Mus musculus |
| 2 | While IDH1 catalyzes the oxidative carboxylation of isocitrate to alpha-ketoglutarate in cytosol, mutated IDH1 proteins possess the ability to change alpha-ketoglutarate into onco-metabolite R(-)-2-hydroxyglutarate (2-HG). | isocitric acid | isocitrate dehydrogenase 1 (NADP+), soluble | Mus musculus |