Title : Second messenger/signal transduction pathways in major mood disorders: moving from membrane to mechanism of action, part II: bipolar disorder.

Pub. Date : 2013 Oct

PMID : 23472710






1 Functional Relationships(s)
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1 The importance of these cascades is highlighted by lithium"s (the gold standard in BD psychopharmacology) ability to inhibit multiple critical loci in second messenger/signal transduction cascades including protein kinase C (involved in the IP3/PIP2 pathway) and GSK-3beta (canonically identified in the Wnt/Fz/Dvl/GSK-3beta cascade). Inositol 1,4,5-Trisphosphate dishevelled segment polarity protein 1 pseudogene 1 Homo sapiens