Title : GRB2-mediated recruitment of THEMIS to LAT is essential for thymocyte development.

Pub. Date : 2013 Apr 1

PMID : 23460737






3 Functional Relationships(s)
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1 In this article, we show that THEMIS and the adapter molecule growth factor receptor-bound protein 2 (GRB2) associate constitutively through binding of a conserved PxRPxK motif within the proline-rich region 1 of THEMIS to the C-terminal SH3-domain of GRB2. Proline growth factor receptor bound protein 2 Homo sapiens
2 In this article, we show that THEMIS and the adapter molecule growth factor receptor-bound protein 2 (GRB2) associate constitutively through binding of a conserved PxRPxK motif within the proline-rich region 1 of THEMIS to the C-terminal SH3-domain of GRB2. Proline growth factor receptor bound protein 2 Homo sapiens
3 In this article, we show that THEMIS and the adapter molecule growth factor receptor-bound protein 2 (GRB2) associate constitutively through binding of a conserved PxRPxK motif within the proline-rich region 1 of THEMIS to the C-terminal SH3-domain of GRB2. Proline growth factor receptor bound protein 2 Homo sapiens