Title : Design and functional evaluation of an optically active μ-opioid receptor.

Pub. Date : 2013 Apr 5

PMID : 23454521






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The forskolin-stimulated adenylate cyclase/cAMP cascade was evaluated by ELISA or western blotting of brain-derived neurotrophic factor (BDNF) and the phosphorylation of cAMP response element binding protein (CREB). Colforsin cAMP responsive element binding protein 1 Homo sapiens
2 The forskolin-stimulated adenylate cyclase/cAMP cascade was evaluated by ELISA or western blotting of brain-derived neurotrophic factor (BDNF) and the phosphorylation of cAMP response element binding protein (CREB). Colforsin cAMP responsive element binding protein 1 Homo sapiens
3 Photoactivation of optoMOR decreased the Ca(2+) influx and inhibited the forskolin-induced cAMP generation, activation of CREB, and BDNF levels in optoMOR-expressing cells similar to the activation of native mu-opioid receptor by DAMGO. Colforsin cAMP responsive element binding protein 1 Homo sapiens