Title : A novel series of tacrine-selegiline hybrids with cholinesterase and monoamine oxidase inhibition activities for the treatment of Alzheimer's disease.

Pub. Date : 2013 Apr

PMID : 23454517






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1 A novel series of tacrine-selegiline hybrids was synthesised and evaluated for application as inhibitors of cholinesterase (AChE/BuChE) and monoamine oxidase (MAO-A/B). Selegiline acetylcholinesterase (Cartwright blood group) Homo sapiens