Title : Induction of sister-chromatid exchanges by polycyclic aromatic hydrocarbons following metabolic activation with phorbol ester-stimulated human polymorphonuclear leukocytes.

Pub. Date : 1990 Mar

PMID : 2343183






1 Functional Relationships(s)
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1 The addition of azide, CuDIPS, or taurine markedly inhibited the induction of SCEs by the combination of BP-7,8-diol and stimulated PMNs, further suggesting the involvement of myeloperoxidase in the activation of the polycyclic aromatic hydrocarbon. Taurine myeloperoxidase Homo sapiens