Pub. Date : 2013 May
PMID : 23423514
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The ratio between FABP5 and CRABPII determines cellular response to physiological level of retinoic acid; tumor cells undergo proliferation with high level of FABP5 and apoptosis with high level of CRABPII. | Tretinoin | cellular retinoic acid binding protein 2 | Homo sapiens |
| 2 | The ratio between FABP5 and CRABPII determines cellular response to physiological level of retinoic acid; tumor cells undergo proliferation with high level of FABP5 and apoptosis with high level of CRABPII. | Tretinoin | cellular retinoic acid binding protein 2 | Homo sapiens |
| 3 | We intended to study FABP5 and CRABPII expression in craniopharyngiomas, to establish craniopharyngioma cell model using explants method, and to study the effect of pharmacological dose of retinoic acid on craniopharyngioma cells. | Tretinoin | cellular retinoic acid binding protein 2 | Homo sapiens |
| 4 | Also, retinoic acid increased CRABPII, and decreased FABP5 and NF-kappaB expression in craniopharyngioma cells. | Tretinoin | cellular retinoic acid binding protein 2 | Homo sapiens |
| 5 | Retinoic acid at pharmacological level induced craniopharyngioma cell apoptosis via increasing FABP5/CRABPII ratio and inhibiting NF-kappaB signaling pathway. | Tretinoin | cellular retinoic acid binding protein 2 | Homo sapiens |