Title : Activation of complement by hemodialysis membranes: polyacrylonitrile binds more C3a than cuprophan.

Pub. Date : 1990 Apr

PMID : 2342244






4 Functional Relationships(s)
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1 In the present study, a method that allows the simultaneous quantification of both fluid phase and membrane bound C3a was used to assess complement activation by PAN and cuprophan. cuprammonium cellulose complement C3 Homo sapiens
2 The results showed that while the serum exposed to cuprophan membranes contained almost five times more C3a than that exposed to PAN, approximately 80 times more C3a was bound to the PAN membranes. cuprammonium cellulose complement C3 Homo sapiens
3 The results showed that while the serum exposed to cuprophan membranes contained almost five times more C3a than that exposed to PAN, approximately 80 times more C3a was bound to the PAN membranes. cuprammonium cellulose complement C3 Homo sapiens
4 Consequently, the total amount of C3a generated in the presence of PAN was higher than that generated in the presence of cuprophan. cuprammonium cellulose complement C3 Homo sapiens