Pub. Date : 2013 Mar 15
PMID : 23416007
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | While HIF-1alpha in hypoxia translocates to the nucleus where it transcribes the target genes including vascular endothelial growth factor (VEGF) mRNA, HIF-1alpha is degraded under normoxia, which involves its proline hydroxylation and subsequent binding to the von Hippel-Lindau protein-Elongin B-Elogin C (VBC) complex. | Proline | hypoxia inducible factor 1 subunit alpha | Homo sapiens |
| 2 | While HIF-1alpha in hypoxia translocates to the nucleus where it transcribes the target genes including vascular endothelial growth factor (VEGF) mRNA, HIF-1alpha is degraded under normoxia, which involves its proline hydroxylation and subsequent binding to the von Hippel-Lindau protein-Elongin B-Elogin C (VBC) complex. | Proline | hypoxia inducible factor 1 subunit alpha | Homo sapiens |