Title : Rationally designed multi-targeted agents against neurodegenerative diseases.

Pub. Date : 2013

PMID : 23410161






1 Functional Relationships(s)
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1 The design strategy for yet another agent, ladostigil, employed the amalgamation of active chemical moieties of the AChE inhibitor rivastigmine, and the monoamine oxidase-B (MAO-B) inhibitor rasagiline, leading to a single compound that targets both enzymes simultaneously. (N-propargyl-(3R) aminoindan-5-yl)-ethyl methyl carbamate monoamine oxidase B Homo sapiens