Title : Interaction of metal chelators with different molecular forms of acetylcholinesterase and its significance in Alzheimer's disease treatment.

Pub. Date : 2013 Jul

PMID : 23408593






3 Functional Relationships(s)
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1 Interaction of metal chelators with different molecular forms of acetylcholinesterase and its significance in Alzheimer"s disease treatment. Metals acetylcholinesterase (Cartwright blood group) Homo sapiens
2 Hence, a comparative study on the effect of metal chelators on both the esterase and AAA activity of AChE globular (G4 and G1) molecular forms was performed. Metals acetylcholinesterase (Cartwright blood group) Homo sapiens
3 Protection studies further revealed that the nature of 1,10-phenanthroline inhibition on AChE is through its direct binding to protein rather than its metal chelation property. Metals acetylcholinesterase (Cartwright blood group) Homo sapiens