Title : Lack of an effect of CYP3A4 and MDR1 gene polymorphisms on colchicine pharmacogenetics in the treatment of Familial Mediterranean fever.

Pub. Date : 2013 Jan 24

PMID : 23408444






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The P-gp/MDR1 multidrug transporter mediates detoxification of numerous drugs, including colchicine, and CYP3A4 is key to the biotransformation of colchicine. Colchicine ATP binding cassette subfamily B member 1 Homo sapiens
2 The P-gp/MDR1 multidrug transporter mediates detoxification of numerous drugs, including colchicine, and CYP3A4 is key to the biotransformation of colchicine. Colchicine ATP binding cassette subfamily B member 1 Homo sapiens
3 We investigated the effects of CYP3A4 and P-gp/MDR1 polymorphisms on bioavailability of colchicine in patients with Familial Mediterranean fever (FMF). Colchicine ATP binding cassette subfamily B member 1 Homo sapiens