Title : The molecular mechanism of action of aspirin, curcumin and sulforaphane combinations in the chemoprevention of pancreatic cancer.

Pub. Date : 2013 Apr

PMID : 23404329






1 Functional Relationships(s)
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1 Results demonstrated that low doses of ASP (1 mM), CUR (10 microM) and SFN (5 microM) (ACS) combination reduced cell viability by ~70% (P<0.001), and also induced cell apoptosis by ~51% (P<0.001) accompanied by activation of caspase-3 and Poly(ADP-ribose) polymerase (PARP) proteins. Aspirin 1-aminocyclopropane-1-carboxylate synthase homolog (inactive) Homo sapiens