Title : 2D- and 3D-QSAR studies of a series of benzopyranes and benzopyrano[3,4b][1,4]-oxazines as inhibitors of the multidrug transporter P-glycoprotein.

Pub. Date : 2013 Feb

PMID : 23400406






1 Functional Relationships(s)
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1 Towards this goal, a series of Benzopyranes and Benzopyrano[3,4b][1,4]oxazines have been synthesized and pharmacologically tested for their ability to inhibit P-gp mediated daunomycin efflux. Daunorubicin ATP binding cassette subfamily B member 1 Homo sapiens