Title : Sex-dependent association between angiotensin-converting enzyme insertion/deletion polymorphism and obesity in relation to sodium intake in children.

Pub. Date : 2013 Mar

PMID : 23398920






4 Functional Relationships(s)
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1 Sex-dependent association between angiotensin-converting enzyme insertion/deletion polymorphism and obesity in relation to sodium intake in children. Sodium angiotensin I converting enzyme Homo sapiens
2 This study investigated whether the ACE insertion/deletion (I/D) polymorphism affects obesity in relation to sodium intake in children. Sodium angiotensin I converting enzyme Homo sapiens
3 D-carrier boys did not show any association with the degree of obesity, whereas D-carrier girls with a high sodium intake exhibited a significant association (odds ratio 0.551, P = 0.042) and a negative correlation between the D allele and obesity as a continuous variable (regression coefficient -3.095, P = 0.020), showing gender-dependent associations between the ACE I/D polymorphism and obesity in relation to sodium intake. Sodium angiotensin I converting enzyme Homo sapiens
4 CONCLUSIONS: These findings demonstrate that the association between the ACE I/D polymorphism and obesity in relation to sodium intake is gender dependent in children. Sodium angiotensin I converting enzyme Homo sapiens