Title : Eicosanoid modulation by the short-chain fatty acid n-butyrate in human monocytes.

Pub. Date : 2013 Jul

PMID : 23398566






1 Functional Relationships(s)
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1 Our results suggest that among many other mediators of eicosanoid signalling n-butyrate massively induces PGE(2) production by increasing the expression of PTGS2 (COX-2) in monocytes following TLR4 and TLR2 activation and induces secretion of LTB(4) and thromboxane B(2). Prostaglandins E mitochondrially encoded cytochrome c oxidase II Homo sapiens