Title : Nicotinamide downregulates gene expression of interleukin-6, interleukin-10, monocyte chemoattractant protein-1, and tumour necrosis factor-α gene expression in HaCaT keratinocytes after ultraviolet B irradiation.

Pub. Date : 2013 Mar

PMID : 23397947






1 Functional Relationships(s)
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1 In this study we investigated whether nicotinamide (NCT), the amide form of vitamin B3, might have a protective function in reducing the expression of interleukin (IL)-1beta, IL-6, IL-8, IL-10, monocyte chemoattractant protein (MCP)-1 and tumour necrosis factor (TNF)-alpha in UV-irradiated keratinocytes. Niacinamide C-X-C motif chemokine ligand 8 Homo sapiens