Pub. Date : 2013 Mar 29
PMID : 23396969
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Intestinal dehydroascorbic acid (DHA) transport mediated by the facilitative sugar transporters, GLUT2 and GLUT8. | Dehydroascorbic Acid | solute carrier family 2, (facilitated glucose transporter), member 8 | Mus musculus |
| 2 | Intestinal dehydroascorbic acid (DHA) transport mediated by the facilitative sugar transporters, GLUT2 and GLUT8. | Dehydroascorbic Acid | solute carrier family 2, (facilitated glucose transporter), member 8 | Mus musculus |
| 3 | Only GLUT2 and GLUT8, known to be expressed in intestines, transported DHA with apparent transport affinities (Km) of 2.33 and 3.23 mm and maximal transport rates (Vmax) of 25.9 and 10.1 pmol/min/oocyte, respectively. | Dehydroascorbic Acid | solute carrier family 2, (facilitated glucose transporter), member 8 | Mus musculus |
| 4 | Maximal rates for DHA transport mediated by GLUT2 and GLUT8 in oocytes were lower than maximal rates for 2-deoxy-d-glucose (Vmax of 224 and 32 pmol/min/oocyte for GLUT2 and GLUT8, respectively) and fructose (Vmax of 406 and 116 pmol/min/oocyte for GLUT2 and GLUT8, respectively). | Dehydroascorbic Acid | solute carrier family 2, (facilitated glucose transporter), member 8 | Mus musculus |
| 5 | Maximal rates for DHA transport mediated by GLUT2 and GLUT8 in oocytes were lower than maximal rates for 2-deoxy-d-glucose (Vmax of 224 and 32 pmol/min/oocyte for GLUT2 and GLUT8, respectively) and fructose (Vmax of 406 and 116 pmol/min/oocyte for GLUT2 and GLUT8, respectively). | Dehydroascorbic Acid | solute carrier family 2, (facilitated glucose transporter), member 8 | Mus musculus |
| 6 | Maximal rates for DHA transport mediated by GLUT2 and GLUT8 in oocytes were lower than maximal rates for 2-deoxy-d-glucose (Vmax of 224 and 32 pmol/min/oocyte for GLUT2 and GLUT8, respectively) and fructose (Vmax of 406 and 116 pmol/min/oocyte for GLUT2 and GLUT8, respectively). | Dehydroascorbic Acid | solute carrier family 2, (facilitated glucose transporter), member 8 | Mus musculus |
| 7 | DHA transport activity in GLUT2- and GLUT8-expressing oocytes was inhibited by glucose, fructose, and by the flavonoids phloretin and quercetin. | Dehydroascorbic Acid | solute carrier family 2, (facilitated glucose transporter), member 8 | Mus musculus |
| 8 | These studies indicate intestinal DHA transport may be mediated by the facilitative sugar transporters GLUT2 and GLUT8. | Dehydroascorbic Acid | solute carrier family 2, (facilitated glucose transporter), member 8 | Mus musculus |