Title : Effects of memantine and melatonin on signal transduction pathways vascular leakage and brain injury after focal cerebral ischemia in mice.

Pub. Date : 2013 May 1

PMID : 23396088






2 Functional Relationships(s)
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1 However, melatonin increased the activation of Akt and reduced the activations of ERK-1/2, p21, p38/MAPK and SAPK/JNK1/2 significantly. Melatonin mitogen-activated protein kinase 3 Mus musculus
2 Moreover, memantine reversed the effects of melatonin on the activation of ERK-1/2 pathway. Melatonin mitogen-activated protein kinase 3 Mus musculus