Title : The compensatory expression of reproductive hormone receptors in the thymus of the male rat following active immunization against GnRH.

Pub. Date : 2013 May 1

PMID : 23395683






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1 In summary, these findings suggest that active immunization against GnRH can up-regulate GnRH receptor and gonadotropin receptor signaling, by stimulating thymic autocrine and paracrine function, whereas the androgen receptor is down-regulated due to a lack of testosterone secretion in the thymus. Testosterone gonadotropin releasing hormone 1 Rattus norvegicus