Title : Simvastatin inhibits ox-LDL-induced inflammatory adipokines secretion via amelioration of ER stress in 3T3-L1 adipocyte.

Pub. Date : 2013 Mar 8

PMID : 23376721






2 Functional Relationships(s)
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1 The aim of this study is to evaluate the effect of simvastatin on the ox-LDL-induced ER stress and expression and secretion of TNF-alpha and MCP-1 in 3T3-L1 adipocytes. Simvastatin tumor necrosis factor Homo sapiens
2 Simvastatin could inhibit ox-LDL-induced ER stress and reduce the expression of TNF-alpha and MCP-1 at mRNA and protien level in dose dependent manner. Simvastatin tumor necrosis factor Homo sapiens