Title : Carvacrol suppresses the expression of inflammatory marker genes in D-galactosamine-hepatotoxic rats.

Pub. Date : 2013 Mar

PMID : 23375034






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1 RESULTS: We found that the mRNA and protein expressions of TNF-alpha, IL-6, iNOS, COX-2 and NF-kappaB were significantly up-regulated in D-galactosamine induced hepatotoxic rats and treatment with carvacrol significantly down-regulated the expressions of these genes showing the mechanism behind the anti-inflammatory activity of carvacrol. Galactosamine tumor necrosis factor Rattus norvegicus