Title : Involvement of PKA and HO-1 signaling in anti-inflammatory effects of surfactin in BV-2 microglial cells.

Pub. Date : 2013 Apr 1

PMID : 23360889






1 Functional Relationships(s)
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1 Surfactin significantly inhibited excessive production of the pro-inflammatory mediators TNF-alpha, IL-1beta, IL-6, monocyte chemoattractant protein-1 (MCP-1), prostaglandin E2 (PGE2), nitric oxide (NO) and reactive oxygen species (ROS), and suppressed the expression of matrix metalloproteinase-9 (MMP-9), inducible NO synthase (iNOS) and cyclooxygenase-2 (COX-2). surfactin peptide interleukin 6 Mus musculus