Title : Rabbit and human liver contain a novel pentacyclic triterpene ester with acyl-CoA: cholesterol acyltransferase inhibitory activity.

Pub. Date : 1990 May 15

PMID : 2335515






2 Functional Relationships(s)
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1 Herein we describe the purification and characterization of a novel pentacyclic triterpene ester from rabbit liver that has ACAT inhibitory activity. triterpene ester sterol O-acyltransferase 1 Oryctolagus cuniculus
2 Both the negatively charged carboxylic acid group of the triterpene moiety and the esterified fatty acid group were necessary for the ACAT-inhibitory activity of the triterpene ester. triterpene ester sterol O-acyltransferase 1 Oryctolagus cuniculus