Pub. Date : 2013 Apr
PMID : 23352980
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | After structure-based drug selection, SGI-1776, ETP-45299, and tryptanthrin were selected as candidates of PIM1 inhibitors that act as radiosensitizers. | Ethionamide | proviral integration site 1 | Mus musculus |
| 2 | Taken together, our findings provided evidence that PIM1-specific inhibitors, SGI-1776, ETP-45299, and tryptanthrin, can act as novel radiosensitizers to enhance the efficacy of radiotherapy by inhibiting irradiation-induced signaling pathway associated with radioresistance. | Ethionamide | proviral integration site 1 | Mus musculus |