Title : The cytosolic adaptor AP-1A is essential for the trafficking and function of Niemann-Pick type C proteins.

Pub. Date : 2013 Apr

PMID : 23350547






1 Functional Relationships(s)
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1 In this study, a yeast three-hybrid system revealed that the NPC1 cytoplasmic tail directly interacts with the clathrin adaptor protein AP-1 via its acidic/di-leucine motif. di-leucine Jun proto-oncogene, AP-1 transcription factor subunit Homo sapiens