Title : Mineralocorticoid receptor-mediated vascular insulin resistance: an early contributor to diabetes-related vascular disease?

Pub. Date : 2013 Feb

PMID : 23349535






1 Functional Relationships(s)
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1 Prevention or restoration of these changes via blockade of aldosterone action in the vascular wall with MR antagonists (i.e., spironolactone, eplerenone) may therefore account for the clinical benefit of these compounds in obese and diabetic patients with cardiovascular disease. Eplerenone nuclear receptor subfamily 3 group C member 2 Homo sapiens