Title : Anthocyanins downregulate lipopolysaccharide-induced inflammatory responses in BV2 microglial cells by suppressing the NF-κB and Akt/MAPKs signaling pathways.

Pub. Date : 2013 Jan 14

PMID : 23344054






4 Functional Relationships(s)
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1 Anthocyanins downregulate lipopolysaccharide-induced inflammatory responses in BV2 microglial cells by suppressing the NF-kappaB and Akt/MAPKs signaling pathways. Anthocyanins nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus
2 Moreover, anthocyanins inhibited nuclear translocation of nuclear factor-kappa B (NF-kappaB) by reducing inhibitor of NF-kappaB alpha degradation as well as phosphorylating extracellular signal-regulated kinase, c-Jun N-terminal kinase, p38 mitogen-activated protein kinase, and Akt. Anthocyanins nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus
3 Moreover, anthocyanins inhibited nuclear translocation of nuclear factor-kappa B (NF-kappaB) by reducing inhibitor of NF-kappaB alpha degradation as well as phosphorylating extracellular signal-regulated kinase, c-Jun N-terminal kinase, p38 mitogen-activated protein kinase, and Akt. Anthocyanins nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus
4 Moreover, anthocyanins inhibited nuclear translocation of nuclear factor-kappa B (NF-kappaB) by reducing inhibitor of NF-kappaB alpha degradation as well as phosphorylating extracellular signal-regulated kinase, c-Jun N-terminal kinase, p38 mitogen-activated protein kinase, and Akt. Anthocyanins nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus