Pub. Date : 2013 Jan 23
PMID : 23343389
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Based on such observations we hypothesized that PPARgamma expression would be repressed in alveolar macrophages from animals bearing granulomas induced by MWCNT instillation. | mwcnt | peroxisome proliferator activated receptor gamma | Mus musculus |
| 2 | RESULTS: In wild-type mice, alveolar macrophage PPARgamma expression and activity were significantly reduced in granuloma-bearing animals 60 days after MWCNT instillation. | mwcnt | peroxisome proliferator activated receptor gamma | Mus musculus |
| 3 | PPARgamma KO mice also demonstrated elevated pro-inflammatory cytokine expression in lung tissue, laser-microdissected lung granulomas, and BAL cells/fluids, at 60 days post MWCNT exposure. | mwcnt | peroxisome proliferator activated receptor gamma | Mus musculus |