Pub. Date : 1990 Apr
PMID : 2333947
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Previously, PKC-activating phorbol esters were shown to increase the specific binding of 125I-ANG II in neuronal cultures. | Phorbol Esters | angiotensinogen | Rattus norvegicus |
| 2 | However, phorbol esters have many biological effects, which may nonspecifically act to increase 125I-ANG II-specific binding. | Phorbol Esters | angiotensinogen | Rattus norvegicus |
| 3 | In the present study, mezerein and teleocidin A, two activators of PKC that are chemically unrelated to phorbol esters, increased the specific binding of 125I-ANG II in a dose- and time-dependent manner with 50% effective dose (ED50) values of 32 and 79 nM, respectively. | Phorbol Esters | angiotensinogen | Rattus norvegicus |