Pub. Date : 2013 Jan 22
PMID : 23339468
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Cadmium induces neuronal cell death through reactive oxygen species activated by GADD153. | Reactive Oxygen Species | DNA damage inducible transcript 3 | Homo sapiens |
2 | The generation of ROS result in the induction of GADD153 is causative of cadmium-induced apoptosis. | Reactive Oxygen Species | DNA damage inducible transcript 3 | Homo sapiens |
3 | Therefore, we conclude that GADD153 sensitizes cells to ROS through mechanisms that involve up-regulation of BAK and enhanced oxidant injury. | Reactive Oxygen Species | DNA damage inducible transcript 3 | Homo sapiens |