Title : Cadmium induces neuronal cell death through reactive oxygen species activated by GADD153.

Pub. Date : 2013 Jan 22

PMID : 23339468






3 Functional Relationships(s)
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Protein Name
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1 Cadmium induces neuronal cell death through reactive oxygen species activated by GADD153. Reactive Oxygen Species DNA damage inducible transcript 3 Homo sapiens
2 The generation of ROS result in the induction of GADD153 is causative of cadmium-induced apoptosis. Reactive Oxygen Species DNA damage inducible transcript 3 Homo sapiens
3 Therefore, we conclude that GADD153 sensitizes cells to ROS through mechanisms that involve up-regulation of BAK and enhanced oxidant injury. Reactive Oxygen Species DNA damage inducible transcript 3 Homo sapiens