Title : Differential processing of let-7a precursors influences RRM2 expression and chemosensitivity in pancreatic cancer: role of LIN-28 and SET oncoprotein.

Pub. Date : 2013

PMID : 23335963






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Overexpression of ribonucleotide reductase subunit M2 (RRM2), involved in deoxyribonucleotide synthesis, drives the chemoresistance of pancreatic cancer to nucleoside analogs (e.g., gemcitabine). Deoxyribonucleotides ribonucleotide reductase regulatory subunit M2 Homo sapiens
2 Overexpression of ribonucleotide reductase subunit M2 (RRM2), involved in deoxyribonucleotide synthesis, drives the chemoresistance of pancreatic cancer to nucleoside analogs (e.g., gemcitabine). Deoxyribonucleotides ribonucleotide reductase regulatory subunit M2 Homo sapiens