Title : Cyclooxygenase-2 generates the endogenous mutagen trans-4-hydroxy-2-nonenal in Enterococcus faecalis-infected macrophages.

Pub. Date : 2013 Mar

PMID : 23321929






2 Functional Relationships(s)
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1 Next, to confirm COX-2 as a source for 4-HNE, we assayed the products generated by recombinant human COX-2 and found 4-HNE in a concentration-dependent manner using arachidonic acid as a substrate. Arachidonic Acid mitochondrially encoded cytochrome c oxidase II Homo sapiens
2 Next, to confirm COX-2 as a source for 4-HNE, we assayed the products generated by recombinant human COX-2 and found 4-HNE in a concentration-dependent manner using arachidonic acid as a substrate. Arachidonic Acid mitochondrially encoded cytochrome c oxidase II Homo sapiens