Title : Nitric oxide suppresses NLRP3 inflammasome activation and protects against LPS-induced septic shock.

Pub. Date : 2013 Feb

PMID : 23318584






1 Functional Relationships(s)
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1 Depletion of iNOS resulted in increased accumulation of dysfunctional mitochondria in response to LPS and ATP, which was responsible for the increased IL-1beta production and caspase-1 activation. Adenosine Triphosphate interleukin 1 beta Mus musculus