Title : Prostaglandin E₂-induced intercellular adhesion molecule-1 expression is mediated by cAMP/Epac signalling modules in bEnd.3 brain endothelial cells.

Pub. Date : 2013 Jun

PMID : 23317035






1 Functional Relationships(s)
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1 PGE2, dbcAMP and 8-Cpt-cAMP induced the phosphorylation of Akt, IkappaB kinase and IkappaBalpha and the translocation of p65 to the nucleus and increased NF-kappaB dependent reporter gene activity, which was diminished by Akti. Dinoprostone nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha Mus musculus