Title : Sirt1 attenuates camptothecin-induced apoptosis through caspase-3 pathway in porcine preadipocytes.

Pub. Date : 2013 Mar 10

PMID : 23313858






2 Functional Relationships(s)
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1 Interestingly, silencing of Sirt1 significantly enhances sensitivity of porcine preadipocytes to camptothecin, which may be due to upregulation of p53, acetylated p53, Bax, cleaved caspase-3 and downregulation of Bcl-2. Camptothecin tumor protein p53 Homo sapiens
2 Interestingly, silencing of Sirt1 significantly enhances sensitivity of porcine preadipocytes to camptothecin, which may be due to upregulation of p53, acetylated p53, Bax, cleaved caspase-3 and downregulation of Bcl-2. Camptothecin tumor protein p53 Homo sapiens