Title : Valproic acid upregulates NKG2D ligand expression through an ERK-dependent mechanism and potentially enhances NK cell-mediated lysis of myeloma.

Pub. Date : 2012 Dec

PMID : 23308050






2 Functional Relationships(s)
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Protein Name
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1 Valproic acid upregulates NKG2D ligand expression through an ERK-dependent mechanism and potentially enhances NK cell-mediated lysis of myeloma. Valproic Acid mitogen-activated protein kinase 1 Homo sapiens
2 These data indicate that increased sensitivity of VPA-treated myeloma cells to NK cell lysis is caused by higher NKG2D ligand expression, resulting from more active ERK signaling pathway. Valproic Acid mitogen-activated protein kinase 1 Homo sapiens