Pub. Date : 2012 Dec
PMID : 23308050
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Valproic acid upregulates NKG2D ligand expression through an ERK-dependent mechanism and potentially enhances NK cell-mediated lysis of myeloma. | Valproic Acid | killer cell lectin like receptor K1 | Homo sapiens |
| 2 | In this study, we tested the effect of valproic acid (VPA), a histone deacetylase (HDAC) inhibitor, on the expression of NKG2D ligands in myeloma cells. | Valproic Acid | killer cell lectin like receptor K1 | Homo sapiens |
| 3 | In this study, we tested the effect of valproic acid (VPA), a histone deacetylase (HDAC) inhibitor, on the expression of NKG2D ligands in myeloma cells. | Valproic Acid | killer cell lectin like receptor K1 | Homo sapiens |
| 4 | These data indicate that increased sensitivity of VPA-treated myeloma cells to NK cell lysis is caused by higher NKG2D ligand expression, resulting from more active ERK signaling pathway. | Valproic Acid | killer cell lectin like receptor K1 | Homo sapiens |