Title : ATPase activity of nucleotide binding domains of human MDR3 in the context of MDR1.

Pub. Date : 2013 Apr

PMID : 23305784






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Although human MDR1 and MDR3 share 86% similarity in their amino acid sequences and are predicted to share conserved domains for drug recognition, their physiological transport substrates are quite different: MDR1 transports xenobiotics and confers multidrug resistance, while MDR3 exports phosphatidylcholine into bile. Phosphatidylcholines ATP binding cassette subfamily B member 4 Homo sapiens
2 Although human MDR1 and MDR3 share 86% similarity in their amino acid sequences and are predicted to share conserved domains for drug recognition, their physiological transport substrates are quite different: MDR1 transports xenobiotics and confers multidrug resistance, while MDR3 exports phosphatidylcholine into bile. Phosphatidylcholines ATP binding cassette subfamily B member 4 Homo sapiens