Title : NOD-scid IL2R γnull mice engrafted with human peripheral blood mononuclear cells as a model to test therapeutics targeting human signaling pathways.

Pub. Date : 2013 Jan 7

PMID : 23294516






1 Functional Relationships(s)
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1 RESULTS: hIgE secretion was induced by IL-4 and inhibited by the IL-4 antagonist Pitrakinra in vivo when formulated with methylcellulose. Methylcellulose immunoglobulin heavy constant epsilon Homo sapiens