Title : Adolescent nicotine sensitization and effects of nicotine on accumbal dopamine release in a rodent model of increased dopamine D2 receptor sensitivity.

Pub. Date : 2013 Apr 1

PMID : 23291224






3 Functional Relationships(s)
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1 In addition, neonatal quinpirole increased the accumbal BDNF in response to nicotine compared to all other groups, and nicotine alone also produced significant increases in striatal and accumbal BDNF. Nicotine brain-derived neurotrophic factor Rattus norvegicus
2 In addition, neonatal quinpirole increased the accumbal BDNF in response to nicotine compared to all other groups, and nicotine alone also produced significant increases in striatal and accumbal BDNF. Nicotine brain-derived neurotrophic factor Rattus norvegicus
3 This study reveals that neonatal quinpirole enhanced adolescent nicotine sensitization, accumbal dopamine overflow, and BDNF protein in response to nicotine, which may be related to changes in the brain"s reward system. Nicotine brain-derived neurotrophic factor Rattus norvegicus