Pub. Date : 2013 Dec
PMID : 23290998
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | PARPs use NAD(+) as substrate and upon cleaving off nicotinamide they transfer the ADP-ribosyl moiety covalently to suitable acceptor proteins and elongate the chain by adding further ADP-ribose units to create a branched polymer, termed poly(ADP-ribose) (PAR), which is rapidly degraded by poly(ADP-ribose) glycohydrolase (PARG) and ADP-ribosylhydrolase 3 (ARH3). | Niacinamide | poly(ADP-ribose) polymerase 1 | Homo sapiens |