Title : [Cytochrome P-450 induction and the subsequent induction of an immune response in rats during the chronic administration of xenobiotics].

Pub. Date : 1990 Jan-Feb

PMID : 2328803






2 Functional Relationships(s)
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1 The long-term administration of xenobiotics carcinogens o-aminoazotoluene (o-AAT) and benz(a)pyrene (BP) to rats was found to cause induction of the liver cytochrome P-450 system which gradually decreases in spite of continued administration of the agents. Benzo(a)pyrene cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus
2 The long-term administration of xenobiotics carcinogens o-aminoazotoluene (o-AAT) and benz(a)pyrene (BP) to rats was found to cause induction of the liver cytochrome P-450 system which gradually decreases in spite of continued administration of the agents. Benzo(a)pyrene cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus