Title : Heterologous expression of CYP102A5 variant from Bacillus cereus CYPPB-1: Validation of model for predicting drug metabolism of human P450 probe substrates.

Pub. Date : 2013 Sep

PMID : 23287855






1 Functional Relationships(s)
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1 In vitro analysis suggested that the purified CYP102A5 metabolizes typical substrates of human CYP2C9, CYP2D6, CYP2E1, and CYP3A4, such as coumarin, propranolol, aniline, chlorzoxazone, p-nitrophenol, and nifedipine. Nifedipine cytochrome P450 family 2 subfamily C member 9 Homo sapiens