Title : A novel secretory pathway for interleukin-1 beta, a protein lacking a signal sequence.

Pub. Date : 1990 May

PMID : 2328723






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Secretion of IL-1 beta is blocked by methylamine, low temperature or serum free medium, and is increased by raising the culture temperature to 42 degrees C or by the presence of calcium ionophores, brefeldin A, monensin, dinitrophenol or carbonyl cyanide chlorophenylhydrazone. Carbonyl Cyanide m-Chlorophenyl Hydrazone interleukin 1 beta Homo sapiens